While sharing the festive cheers we are very excited to restart HDR UK Cambridge Seminar Series in the new University of Cambridge Heart and Lung Research Institute (HLRI) located at the Addenbrooke’s site.
All seminars will be held in a hybrid environment, providing a wonderful opportunity to meet speakers in-person (In Person Tickets at the HLRI (0.R088-89 Meeting room) and/or join the exiting discussions virtually.
Keeping up the Holiday spirts Brunch – Lunch will be served before the talk (maybe some mince pie too)
Our first guest speaker is Professor Bhramar Mukherjee (University of Michigan)
Bhramar Mukherjee is John D Kalbfleisch Collegiate Professor and Chair of Biostatistics at the University of Michigan School of Public Health. She is also a professor of Epidemiology and Global Public Health at the University of Michigan. She is currently a visiting By Fellow at the Churchill College, Cambridge University and a Visiting Scholar at the MRC Biostatistics Unit.
Title: Analysis of Genetics linked EHR data: Understanding Selection Bias and Phenotyping Error
“In this talk I will share a decade of experience and excitement of being involved with the Michigan Genomics Initiative, a longitudinal biorepository at the University of Michigan Health System, containing administrative healthcare data linked with genetic markers and many other external data sources on nearly 100,000 participants. This is a rich dataset with large p and large n. However, a perioperative recruitment strategy induces selection bias in the analytic sample. In addition, we have an incomplete capture of disease history leading to phenotype misclassification. I will present strategies to understand and reduce bias when these two sources are at play. Examples from COVID-19 and Cancer will be used to illustrate that foundational principles of study design and sampling are critical to turn big data into reliable knowledge.”
Looking forward to see you all at 9th of December
HDR UK Cambridge