OpenSAFELY is a secure, transparent, open-source software platform for analysis of electronic health records data. All platform activity is publicly logged. All code for data management and analysis is shared, under open licenses and by default, for scientific review and efficient re-use.
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OpenSAFELY is a set of best practices encoded as software. It can be deployed to create a Trusted Research Environment (TRE) alongside appropriate database, compute, governance, and administrative elements; or it can be deployed as a privacy-enhancing layer on any existing secure database or TRE.
OpenSAFELY software is currently deployed within the secure data centres of the two largest electronic health record providers in the NHS, to support urgent research into the Covid-19 emergency: thereby creating OpenSAFELY-TPP and OpenSAFELY-EMIS. OpenSAFELY helps the NHS minimise the sharing of confidential patient information.
OpenSAFELY support National Core Study research via the Longitudinal Health and Wellbeing and Data and Connectivity National Core Studies