The diagnostic accuracy of OCT angiography in naive and treated neovascular age-related macular degeneration: a review.
31 October 2018
Perrott-Reynolds R, Cann R, Cronbach N, Neo YN, Ho V, McNally O, Madi HA, Cochran C, Chakravarthy U.
Eye volume 33, pages274–282(2019)
Optical coherence tomography angiography (OCTA) is a non-invasive retinal imaging innovation that has been gaining popularity for the evaluation of the retinal vasculature. Of clinical importance is its current use either as an alternative or in conjunction with conventional dye-based angiography in neovascular age-related macular degeneration. OCTA is not without limitations and these include image artefact, a relatively small field of view and failure of the segmentation algorithms, which can confound the interpretation of findings. While there are numerous publications on OCTA in neovascular AMD, few have examined the diagnostic accuracy of this new technology compared with the accepted gold standard of fundus fluorescein angiography (FFA). In this review, we summarise the literature on the clinical application of OCTA in nAMD. In particular, we have reviewed the published articles that have reported the sensitivity and specificity of OCTA in the diagnosis of nAMD, and those that have described and or correlated the morphological findings and compared them to dye-based angiography.
‘It’s like the bad guy in a movie who just doesn’t die’: A qualitative exploration of young people’s adaptation to eczema and implications for self-care.
25 April 2019
Ghio D, Muller I, Greenwell K, Roberts A, McNiven A, Langan SM, Santer M. British Journal of Dermatology, Volume 182, Issue 1 Background Eczema is a common childhood inflammatory skin condition,...
A semi-active human digital twin model for detecting severity of carotid stenoses from head vibration-A coupled computational mechanics and computer vision method
15 January 2019
Chakshu NK, Carson J, Sazonov I, Nithiarasu P International Journal for Numerical Methods in Biomedical Engineering (2019) 35(5):e3180 In this work, we propose a methodology to detect the severity...
Annotating and detecting phenotypic information for chronic obstructive pulmonary disease.
26 April 2019
Ju M, Short AD, Thompson P, Bakerly ND, Gkoutos GV, Tsaprouni L, Ananiadou S. JAMIA Open, Volume 2, Issue 2, July 2019, Pages 261–271 Objectives Chronic obstructive pulmonary disease (COPD)...