Research Case Studies
Case study examples of how we have enabled research across the UK.
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EMPA-KIDNEY trial: Effect of empagliflozin on chronic kidney disease progression
EMPA-KIDNEY is an international clinical trial by Oxford Population Health scientists in collaboration with academics spanning eight countries. The study recruited over 6000 participants to...
Vitamin D supplements fail to reduce risk of COVID-19
Large-scale clinical trial shows that a test-and-treat approach to correcting vitamin D deficiency did not reduce risk of COVID-19 or other acute respiratory infections.
COVID-19 hospitalisations among school-age children with underlying health conditions
A population-level study of SARS-CoV-2 infections and COVID-19 hospitalisations among school age children with certain underlying health conditions provided essential data for vaccination decisions.
Revealing the risk of serious bleeding and clotting events following COVID-19 infection and vaccination
A UK wide research group investigated the risk of serious blood clotting or bleeding after vaccination and COVID-19 infection in Wales and provided vital data for policy makers and public reassurance.
A swifter, simpler approach to finding the right patient records for research
Practical help for teams wanting to adopt SNOMED CT.
Investigating the links between father chemotherapy and gene mutation rates in children
Research into families with high gene mutation rates, that could lead to rare diseases, has found a link to the biological father receiving certain chemotherapy treatments.
Study into significant drop in cancer diagnoses in Wales during the COVID-19 pandemic
Researchers have looked at the impact of the COVID-19 pandemic on female breast, colorectal and non-small cell lung cancer incidence, stage and healthcare pathway to diagnosis during 2020 in...
COVID-19 mortality risk for inflammatory arthritis patients: a cohort study using SAIL Databank
A study of inflammatory arthritis (IA) patients found that shielding reduced the incidence of COVID-19. IA was not associated with an increased risk of dying within 28 days, but being vulnerable...
COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records
In May, the HDR UK Impact Commitee selected Thygsen et al.'s paper as the Open Impact Publication of the Month for its impactful use of large datasets to track the impact of the COVID-19 pandemic