Identifying Homogeneous Patterns of Injury in Paediatric Trauma Patients to Improve Risk-Adjusted Models of Mortality and Functional Outcomes.
31 January 2020
Dipnall JF, Gabbe BJ, Teague WJ, Beck B.
International journal of environmental research and public health, (2020) pg 892
Injury is a leading cause of morbidity and mortality in the paediatric population and exhibits complex injury patterns. This study aimed to identify homogeneous groups of paediatric major trauma patients based on their profile of injury for use in mortality and functional outcomes risk-adjusted models. Data were extracted from the population-based Victorian State Trauma Registry for patients aged 0–15 years, injured 2006–2016. Four Latent Class Analysis (LCA) models with/without covariates of age/sex tested up to six possible latent classes. Five risk-adjusted models of in-hospital mortality and 6-month functional outcomes incorporated a combination of Injury Severity Score (ISS), New ISS (NISS), and LCA classes. LCA models replicated the best log-likelihood and entropy > 0.8 for all models (N = 1281). Four latent injury classes were identified: isolated head; isolated abdominal organ; multi-trauma injuries, and other injuries. The best models, in terms of goodness of fit statistics and model diagnostics, included the LCA classes and NISS. The identification of isolated head, isolated abdominal, multi-trauma and other injuries as key latent paediatric injury classes highlights areas for emphasis in planning prevention initiatives and paediatric trauma system development. Future risk-adjusted paediatric injury models that include these injury classes with the NISS when evaluating mortality and functional outcomes is recommended.
Antenatal exposure to solar radiation and learning disabilities: Population cohort study of 422,512 children
8 July 2019
Hastie CE, Mackay DF, Clemens TL, Cherrie MPC, King A, Dibben C, Pell JP Scientific Reports (2019) 9(9356):1-9 Learning disability varies by month of conception. The underlying mechanism is...
Causes of death among homeless people: a population-based cross-sectional study of linked hospitalisation and mortality data in England
11 March 2019
Aldridge RW, Menezes D, Lewer D, Cornes M, Evans H, Blackburn RM, Byng R, Clark M, Denaxas S, Fuller J, Hewett N, Kilmister A, Luchenski S, Manthorpe J, McKee M, Neale J, Story A, Tinelli M,...
Determinants of Transmission Risk During the Late Stage of the West African Ebola Epidemic
3 April 2019
Robert A, Edmunds WJ, Watson CH, Henao-Restrepo AM, Gsell PS, Williamson E, Longini IM, Sakoba K, Kucharski AJ, Touré A, Nadlaou SD, Diallo B, Barry MS, Fofana TO, Camara L, Kaba IL, Sylla L,...